Paliperidone for Treatment of Schizophrenia
نویسندگان
چکیده
منابع مشابه
Paliperidone for treatment of schizophrenia.
In short-term studies, oral paliperidone is an antipsychotic that is more efficacious than placebo. We found its adverse effects to be similar to those of its parent compound, risperidone, with movement disorders, weight gain, and tachycardia all more common with paliperidone than placebo. In addition, paliperidone is associated with substantial increases in serum prolactin that may be associat...
متن کاملOnce-monthly paliperidone injection for the treatment of schizophrenia
Paliperidone palmitate is a new long-acting antipsychotic injection for the treatment of acute and maintenance therapy in schizophrenia. Paliperidone (9-hydroxyrisperidone) is the major active metabolite of risperidone and acts at dopamine D(2) and serotonin 5HT(2A) receptors. As with other atypical antipsychotics, it exhibits a high 5HT(2A):D(2) affinity ratio. It also has binding activity as ...
متن کاملPaliperidone in the treatment of Schizophrenia: An overview
The schizophrenia is a psychiatric disease, characterized by symptoms alterating the mind, behaviour and emotion. The terms antipsychotic and neuroleptic define a group of drugs mainly used to treat schizophrenia. The antipsychotics may be divided into two classes: classic or typical and atypical. The paliperidone, the major metabolite of risperidone, shares with the native drug the characteris...
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چکیده ندارد.
15 صفحه اولCost-Effectiveness of Paliperidone Palmitate Versus other Antipsychotics for the Treatment of Schizophrenia in France.
METHODS • Schizophrenia is a severe mental disorder, characterized by profound disruptions in thinking and affecting language, perception, and the sense of self.[1] This disabling and emotionally devastating illness is manifested by ‘positive’ (e.g. delusion, hallucinations) and ‘negative’ (e.g. blunted affect, alogia) symptoms. • In 2005, the prevalence of schizophrenia patients in France was ...
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ژورنال
عنوان ژورنال: Schizophrenia Bulletin
سال: 2007
ISSN: 0586-7614,1745-1701
DOI: 10.1093/schbul/sbn015